This study investigates the determinants of neighborhood satisfaction in Shanghai focusing on objective neighborhood features and uncovers native-migrant differences. A conceptual framework that considers two dimensions of spatial accessibility to urban services, i.e., revealed accessibility and potential accessibility, as well as the mix distribution of urban services in the neighborhood, is adopted. Combining georeferenced survey data from the Shanghai Urban Neighborhood Survey with point-of-interest (POI) data from a cataloging website, revealed spatial accessibility to urban services is assessed by self-reported presence of facilities near residential neighborhood, potential spatial accessibility is measured by the number of POI within a 500m radius from home location, and urban service mix is indexed using the Shannon entropy. The results show that Shanghai-natives are less satisfied with their residential neighborhoods than migrants, and the least satisfied Shanghai-natives tend to be richer, have a longer duration of residency in the current neighborhood, and live in neighborhoods with more restaurants around and a higher level of urban service mix. Revealed accessibility to cultural and sports facilities positively relates to neighborhood satisfaction, with no native-migrant difference in the positive relationship. However, potential accessibility to more restaurants and a higher level of urban service mix relate to lower neighborhood satisfaction, with a stronger negative relationship for Shanghai-natives than migrants. The findings of this study have important implications for urban planning and development practices in rapidly urbanizing cities in China and beyond.